Gadolinium-based Contrast Agents for Magnetic Resonance Imaging (MRI): Drug Safety Communication - FDA Evaluating the Risk of Brain Deposits With Repeated Use This is a preliminary report on possible problems with getting too many MRIs with Gadolinium. Most (or all) brain tumor scans use Gadolinium. I would think that the benefit of knowing how the tumor is doing far outweighs the risk when the patient is known to have a brain tumor or has symptoms of a brain tumor. I know many people who have had over 20 scans with Gadolinium with no apparent problems related to it. However, it may have an impact on MRIs that are used to screen for brain tumors. They have to figure out what the actual risk of using the Gadolinium is compared to the risk of not finding a brain tumor before symptoms appear. That is going to be close - might tilt toward NOT doing screenings.