New Consensus Recommendations Announced for Standardized Imaging Protocol in Brain Tumor Clinical Trials This new standard should be used for all new clinical trials, and if possible, even for brain tumor patients outside of clinical trials. It will allow for a better comparison from scan to scan by minimizing the differences between MRI scanners. Currently, you can do a scan in 1 MRI machine, and immediately do another scan in a different machine and the results could be off by as much as 20-25%. This makes it impossible to tell if you are doing better, worse or no change.
This standardization effort was the result of the Jumpstarting Brain Tumor Drug Development Coalition, which was started by the National Brain Tumor Society. The Musella Foundation, as well as ABC2 and the Society For Neuro-oncology are also participants in the coalition.