FDA Approves NextSource's Brain Tumor Treatment This is an old drug - CCNU - but a new capsule size was just approved by the FDA. It is commonly used in combination with Avastin. The standard dose is 130mg/m2 which for a 200 pound 6' tall person works out to about 275 mg... They already had capsules of 100mg, 40 mg and 10mg. SO I guess this allows for finer control of the dose - however, some insurance companies charge a copay on each capsule size.
Oncoceutics Begins Fifth Clinical Trial for ONC201 This is a new clinical trial for recurrent GBMs. This is a new approach, with a new target. It is an oral medication. See oncoceutics.com/therapeutic-approach/
for details on the mechanism. I will be watching this closely - as the Musella Foundation gave them a research grant a few years ago to help do the preclinical work on this new drug - which came out pretty good!
