First Patient Enrolled in RTOG Trial of Optune® together with Bevacizumab for Patients with Bevacizumab-Refractory Recurrent Glioblastoma Interesting combination. I would guess the concept they are going after is that Avastin, when it fails, doesn't just stop working - it just doesn't work enough but still is slowing down the tumor. If you add Optune, perhaps the combination could be strong enough to stop the tumor. Hate to say, but it may make more sense to just start Optune at the start - right after radiation - on newly diagnosed people. For those that missed that opportunity, this trial makes sense.
[Disclaimer: Novocure is a sponor of our organizaiton]
Diffusion Pharmaceuticals seeks Wall Street investment while staying local This is an important trial. In the phase 2 trial, on newly diagnosed GBM patients who only had biopsies - not subtotal resection or complete resection, they had "in patients with inoperable tumors, who demonstrated a 380 percent increase in survival at two years."
This is do important that I am including it in my presentation to the FDA next week as an example of a drug that needs to be approved quickly!
