Human CAR-T Cell Glioblastoma Trial Generates Clues for Improving Treatment This was too small to tell if the treatment works, but it did prove that these cells can cross the blood brain barrier- which is a major step forward. CAR-T cell therapy is one of the most exciting new therapies available. Recently the first CAR-T cell therapy for leukemia was approved by the FDA, after trials showing very high long term remission rates after a single injection!