Thoughts on "Right To Try" These are my thoughts on the right to try law. The Senate passed it already and the House is considering it.
A cold virus could extend lives of some brain cancer patients, MD Anderson study finds This is impressive. After a single injection, they had a complete response to a recurrent gbm, and 20% of the patients did much better than expected - although unfortunately they all died. This is a step forward - it has to be fined tuned: optimize the delivery and schedule of it and see which drugs can make it work better.
Phase II, Open-Label, Randomized, Multicenter Trial (HERBY) of Bevacizumab in Pediatric Patients With Newly Diagnosed High-Grade Glioma. This trial shows why we need to test treatments in kids and not just assume that they will work the same as in adults. This trial compares the standard of radiation and temodar with and without Avastin, for newly diagnosed high grade glioma. In previously reported trials on adults, there was a pretty good increase in progression free survival with just about no increase in overall survival. In this study with children, they found that adding Avastin decreased both the progression free survival and overall survival, and there were more side effects in the Avastin group.
[Disclosure: Genetech is a sponsor of our organization]
