Reinforcement Learning for Optimal Scheduling of Glioblastoma Treatment With Temozolomide This article looks at alternate dosing schedules for Temozolomide. They think an every other day schedule might be better than the standard that they use in their country (which is different than what is standard here in the USA). This is only a computer modeling and has not been tried in people yet. I like to see research on using our existing treatments better. This should be tested in lab animals first, then if successful, a human trial.
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Lessons Learned in Using Laser Interstitial Thermal Therapy (LITT) for Treatment of Brain Tumors: A Case Series of 238 Patients From A Single Institution Lessons Learned in Using Laser Interstitial Thermal Therapy (LITT) for Treatment of Brain Tumors: A Case Series of 238 Patients From A Single Institution LITT is a a minimally invasive procedure using laser energy delivered through a catheter, under MRI guidance to destroy tumor or radiation necrosis. It can sometimes be used when an open surgery is too dangerous and is much easier for the patient than a traditional surgery. This article shows how important experience is when using this relatively new technique. The first 100 patients they used it on had a much higher (15.5% vs 4.4%) chance of permanent motor deficits than the subsequent group of 138 patients. Some of the difference might also be explained by advances in the equipment and software.
