No OS Boost With Opdivo in Recurrent Glioblastoma This study shows that using Opdivo by itself doesn't work well in recurrent glioblastoma. My thoughts are that something else is needed to trigger the immune response, then Opdivo can enhance that response. It might be something as simple as Optune - by killing cells, neoantigens are released and the immune system gets primed. Opdivo could theoretically enhance that immune response. Or a vaccine. Or more radiation. These things need to be tested further!
