Latest News

• Musella Foundation awards two more brain tumor research grants!         These 2 grants are exciting.  We did a webinar about the Gallium Maltolate project. See https://virtualtrials.org/video2021.cfm?video=202105 This is a new approach to treating brain tumors. They are trying it on Glioblastomas but it may work for most cancer types - not just brain tumors. To be honest, I never heard of uORFs before this grant application came in. I had to research what it is, and found that they regulate gene expression and thereby can influence how much of a protein is made by the cell.  Dysfunction of the uORFs may be the underlying cause of many cancers, and very little research has been done into the connection between uORFs and cancer. The researcher chose to work on Group 3 Medulloblastomas because it is known that these tumors rely heavily on translational regulation. If this project is successful it may lead to breakthroughs in all cancer types.
  



• Heterogeneous delivery across the blood-brain barrier limits the efficacy of an EGFR-targeting antibody drug conjugate in glioblastoma         We had high expectations for this treatment, and were shocked when it failed the clinical trial.  this article may explain why and opens the door to try again using a way to get the treatment into the brain - perhaps with focused ultrasound, or other ways around the blood brain barrier.  
  



• Market Research Opportunity for Patients and Caregivers        We have worked with this organization for a few years. They have a survey for Glioblastoma patients and / or the caretakers, where they will pay you to participate. They also donate to the Musella Foundation!  Please participate if you can!