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Musella Foundation Logo and Name of Email Blast
Thursday, September 14, 2023
Issue 5939
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Advocacy
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NEW: July 2023
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Latest News

  • xCures Platform advances progress on the White House Cancer Moonshot mission to end cancer as we know it.        
    I'm incredibly proud to be a part of xCures. The White House recently highlighted our work in a fact sheet about the Cancer Moonshot initiative, specifically mentioning our contributions to Diffuse Midline Glioma (DMG) and DIPG research. xCures operates a regulatory-grade registry that meticulously tracks data on patients with DMG, DIPG, and various other diseases. We swiftly collect and organize all of the patient's medical records. This de-identified data is then made freely available to researchers, benefiting both the research community and the patients involved.
     
    For instance, this data can serve as a contemporaneous matched control group, thereby eliminating the need for placebos in pediatric brain tumor trials. This is particularly useful in phase 2 trials, where it can act as a control group to provide a more accurate understanding of a treatment's impact on the disease. One of the most common reasons treatments excel in phase 2 but fail in phase 3 trials is the use of poorly matched historical controls in the former, leading to an inflated perception of efficacy. Our project aims to prevent such outcomes, potentially saving lives and reducing both time and financial costs for pharmaceutical companies.
     
    Disclaimer: I am a paid consultant for xCures and also one of the company's founders.

  • Deep vein thrombosis as a side effect of cancer: 9 things to know??        
    Patients with brain tumors and their caregivers should be aware of the symptoms of deep vein thrombosis (DVT). The initial symptoms of DVT in cancer patients include swelling, redness, and pain in one or both arms or legs; abdominal pain; or swelling or redness around the port site. The major risk is that the clot could dislodge and travel to the lungs, leading to a potentially fatal pulmonary embolism. Symptoms of a pulmonary embolism include shortness of breath, chest pain, lightheadedness, and difficulty breathing.
     
    If you suspect you may have a blood clot or pulmonary embolism, seek immediate medical attention. Contact your doctor and inform them of your symptoms. If you're unable to reach your doctor, go to the emergency room and clearly state that you suspect you have a blood clot or pulmonary embolism. This is a medical emergency.


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The article commentaries are the opinions of Al Musella, DPM and do not represent the official position of the Musella Foundation. Copyright 1992-2023 Musella Foundation - All rights reserved. No part of the Brain Tumor News Blast can be reproduced without the express written permission of the Musella Foundation.