Al's Comment:

 Convection enhanced delivery is a way of giving drug directly to the tumor bed, bypassing the blood brain barrier.   This article reviews all of the CED trials to date, and some of them had impressive results. They discuss the use of an implantable pump which allows continuous ongoing delivery of the drug. Bottom line is this method of delivery is relatively safe, and makes the treatments more effective. On the downside, it is invasive which carries some risks.    I think we will soon see major breakthroughs using this methodology.

Posted on: 03/19/2021

Convection Enhanced Delivery of Topotecan for Gliomas: A Single-Center Experience


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