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This study shows that the tumor recurs further away from the primary tumor when using Optune than without Optune. The significance of this is that the new tumor grows in areas that have a low dose of tumor treating fields. First - this proves that Optune has an effect - it prevents the regrowth in areas of high field strength. However, it also points to the fact that other treatments are needed along with Optune to prevent recurrences - or the arrays have to be aimed differently to cover the areas more likely to get a recurrence.