Al's Comment:

 This combination makes a lot of sense. A checkpoint inhibitor by itself has not been shown to help Glioblastomas.   They enhance immune reactions, but they require something to trigger that immune reaction.  Optune could provide that trigger, as it kills cells, the immune system is triggered and the Keytruda should be able to  enhance that immune response. A small pilot study showed good results. 


Posted on: 05/27/2022

Novocure Announces Clinical Collaboration with MSD on a Registrational-Intent Study to Evaluate Tumor Treating Fields Together with KEYTRUDA® (pembrolizumab) in Newly Diagnosed Glioblastoma

 


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