Al's Comment:

 Diffuse midline gliomas with the H3K27M mutation are among the worst of the worst brain tumors, even if the diagnosis is not glioblastoma.. In this meta analysis, they found that these patients only have a median overall survival of 10 months and although radiation helps, no chemotherapies they tested helped at all. This is a huge unmet need.

Posted on: 06/14/2022

H3K27M-Altered Diffuse Midline Gliomas Among Adult Patients: A Systematic Review of Clinical Features and Survival Analysis


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