Al's Comment:

 This shows the importance of having genetic testing done on your tumor.  The BRAF V600E mutation is rare, but when found, this drug combination is useful.  This mutation is more commonly found in kids with low grade brain tumors, but also sometimes in adult glioblastoma. Although approved for kids with low grade tumor, it can be used off label for adults and kids with high grade tumors when they have this mutation.

Posted on: 03/17/2023

FDA Approves Dabrafenib Plus Trametinib for Pediatric BRAF V600E-Mutant Low-Grade Glioma


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