Sponsored by
We gave a grant last year for a preclinical project exploring heat-sensitive liposomes (Thermodox®) combined with laser interstitial thermal therapy (LITT). This year, we awarded a $50,000 grant to Dr. Brice Martin to at Weill Cornell to investigate low-intensity focused ultrasound (LIFU) + Thermadox® for diffuse midline glioma (DMG). The special heat-activated chemotherapy formulation of Thermodox® helps bypass the blood brain barrier and deliver targeted therapy directly to the tumor site. This approach could significantly improve the safety and effectiveness of chemotherapy, and our support will help build the preclinical groundwork needed to move this technology into human trials for GBM and DMG.