The Musella Foundation For Brain Tumor Research & Information is now accepting applications for brain tumor research grants. We have set up our system to make it easier and faster for researchers to get the money they need. There is no deadline, no timetables, and minimal paperwork required. We will consider applications as soon as they are submitted. We will post the proposal on our website where our grants committee will evaluate it. (Do NOT include anything that is secret. It WILL be posted on the web!) If the project is found acceptable by our grants committee and we have the money available, we will quickly approve the request and send a check in days. We also encourage other brain tumor organizations and even individuals to look through these proposals for projects that they would like to fund. Other organizations can feel free to directly give grants to any projects they see here - or perhaps partner with us to fund a project that we both can't afford individually, and individuals can fund projects by making a donation and specifying which projects they want it to go to.

The application process consists of 2 parts: (To request the application, go to our feedback form and ask for the grant application!)

1. You submit a grant proposal of about 1 page describing what you want to do, why you think it might work on brain tumors, specific tumor types or age groups that may be involved, and how much money you need. Leave out the "fluff" such as statistics on how bad brain tumors are. We know.
2. IF your project is selected as a candidate for approval, we will give you a short list of questions to answer. We don't want to make you take time from research to fill out paperwork.

TO APPLY: All doctors in our database have a private control panel where they can edit thier contact information and list thier trials. The application is at the bottom of the control panel. If you aren't already in our database, go to: Virtualtrials.com and click on "ABOUT US" then "ADD A TRIAL" then register as a new user. Feel free to call us at 888-295-4740 if you have any problems or questions!

Our recent grant awards include:

• 2009
• $49,938 to Dr Zagzag at NYU Medical Center for a project: Combined Anti-Angiogenic and Anti-Invasive Therapy for Gliomas. This grant was funded by our "Donald Klein Memorial Fund", individual donations as well as a generous donation from Unlocking Brain Tumors via the Grey Ribbon Crusade!

• 2008
• $5,000 to the Brad Kaminsky Foundation (as part of the Grey Ribbon Crusade) - for project: Preclinical Studies on Convection Enhanced Delivery of Carbolatin in Combination with Photon Irradiation for the Treatment of Gliomas
• $8,000 to the Brad Kaminsky Foundation (as part of the Grey Ribbon Crusade) - for project: Heroes of Hope Race for Research to raise money for immunotherapy program at UCLA
• $20,000 to the Brad Kaminsky Foundation (as part of the Grey Ribbon Crusade) - for project: Preclinical Studies on Convection Enhanced Delivery of Carbolatin in Combination with Photon Irradiation for the Treatment of Gliomas
• $10,000 to the Pediatric Brain Tumor Program at Columbia Presbyterian Medical Center, NY for project involving Ruta-6 in rats.
• $20,000 to Dr Muh at Emory for project titled:A novel pan PI3-kinase inhibitor (SF1126) in the treatment of medulloblastoma. This was the first grant given via the Heroes of Hope coalition, where brain tuymor organizations work together to quickly fund projects. Our contribution for this project was $6,667. The Wittmer Foundation and Unlocking Brain Tumors, Inc each also contributed $6,667.
• $60,000 to Dr Hideho Okada at the University Of Pittsburgh for work on a new vaccine for low grade oligodendrogliomas. Click HERE for a video about his current vaccine for GBMs This grant was made possible through the Oligo Fund, and the Heroes Of Hope coalition (greyribboncrusade.org), specifically, with the help of Unlocking Brain Tumors, George Bein and the Oligo online support group!

• 2007
• $40,000 to Dr Hideho Okada at the University Of Pittsburgh for work on a new vaccine for low grade glioma. Click HERE for a video about his current vaccine for GBMs
• $25,000 grant to F. Avraham Dilmanian, Ph.D. at Brookhaven National Lab, NY for the project titled: "Stereotactic Microbeam Radiation Therapy of a rat brainstem gliosarcoma as a surrogate for optic glioma" - (This was the 4th payment for a project started Dec 2006)
• $25,000 grant to F. Avraham Dilmanian, Ph.D. at Brookhaven National Lab, NY for the project titled: "Stereotactic Microbeam Radiation Therapy of a rat brainstem gliosarcoma as a surrogate for optic glioma" - (This was the third payment for a project started Dec 2006). Click HERE to see an article about the project.
• $20,000 grant to F. Avraham Dilmanian, Ph.D. at Brookhaven National Lab, NY for the project titled: "Stereotactic Microbeam Radiation Therapy of a rat brainstem gliosarcoma as a surrogate for optic glioma" - (This was the second payment for a project started Dec 2006)

• 2006
• $15,000 grant to F. Avraham Dilmanian, Ph.D. at Brookhaven National Lab, NY for the project titled: "Stereotactic Microbeam Radiation Therapy of a rat brainstem gliosarcoma as a surrogate for optic glioma" - Note: this grant was a joint effort between the Musella Foundation and the Lauren's First and Goal Foundation
• $50,000 to Robert Prins. PhD, at UCLA Medical Center, for the project titled: “Genetic profiling and immunotherapeutic targeting of Optic Gliomas”
• $50,000 to Timothy E. Van Meter, PhD at Virginia Commonwealth University for a project entitled "A Molecular Signature of Pediatric Optic Glioma"

• 2005
• $80,000 grant to Dr Linda Liau at UCLA start a phase 1 trial of recombinant Listeria Monocytogenes (rLM) live bacterial vectors for targeting tumor-associated antigens expressed by malignant gliomas that are otherwise inoperable
• $150,000 milestone payment toward $500,000 grant to Cedar Sinai for "A Phase I Trial of Tumor Associated Antigen-Pulsed Dendritic Cell Immunotherapy for Patients with Brain Stem Glioma" - to start the trial on patients! Previous portion of grant was for creation of the vaccine therapy.
• $10,000 to Dr. Garret Yount at the California Pacific Medical Center Research Institute for project: "Brain Tumor Stem Cell Response to Novel Anti-Cancer Agents"
• $10,000 to Dr. Peter Burger and Dr. Charles Eberhart at the Johns Hopkins School Of Medicine, for Pilomyxoid / Pilocytic Research Study. Other organizations are working together with us to fund this $60,000 project!
• 2004
• $120,000 to Dr Linda Liau at UCLA for the Development of recombinant Listeria Monocytogenes (rLM) live bacterial vectors for targeting tumor-associated antigens expressed by malignant gliomas (including Diffuse Intrinsic Pontine Gliomas) that are otherwise inoperable.*
• $500,000 was awarded to Dr Keith Black and Dr John Yu at Cedas Sinai for "A Phase I Trial of Tumor Associated Antigen-Pulsed Dendritic Cell Immunotherapy for Patients with Brain Stem Glioma" , which will pay for the first 2 years of a possible 4 year study. First payment of $100,000 was made.
• $50,000 to Dr Roberta Hayes at Cabrini Medica Center for "Generation of an Immunologic Vaccine against EGFR mutants for inoperable brain tumors: brainstem gliomas and gliomatosis"
• $50,000 to Dr. Kellie J. Nazemi and the Dana-Farber Cancer Institute for "Investigation into the Pathways that Regulate Growth of Infratentorial (brainstem) Brain Tumors"
• $30,000 to Dr. Erwin VanMeir at the Winship Cancer Institute at Emory University for "Investigation of the role of IL-8 expression in gliomagenesis"
• 2003
• $50,000 to Dr. Waldemar Debinski for pre-clinical work on Glioblast-13, a new IL-13-based cytotoxin for malignant glioma.
• $40,000 to Dr. Paul Zeltzer to research a book on brain tumors for patients
• $6,000 to Dr. Roberta Hayes to purchase a freezer used to store cell cultures for an immunotherapy research project (IL-2 + LAK Cells).

	Proposals for brain tumor research grants
	$200,000.00				Virotherapy for Malignant Gliomas
	$150,000.00				Phase I trial of combination imiquimod/DCVax for low-grade gliomas
	$140,000.00				Stereotactic Microbeam Radiation Therapy for brain tumors in a rabbit model.
	$100,000.00				Signal Transduction Determinants in Optic Glioma Invasion
	$100,000.00				Development of novel delivery mechanisms for oncolytic viral therapy of GBMs.
	$100,000.00				Why not an early detection and treatment strategy for brain tumor?
	$100,000.00				Mechanistic Studies on Purified Compounds from Alpinia officinarum Targeted Against Glioma
	$100,000.00				Early Clinical Screening of Children for the Diagnosis of Neurofibromatosis Type 1 (NF-1) with study of Biologic Correlates for Optic Gliomas
	$65,000.00				Rat immunity Modification to generate protective anti-tumor immunity
	$60,000.00				The Pilocytic/Pilomyxoid Research Study
	$56,880.00				Molecular and Cellular Determinants of Optic Glioma Formation
	$54,483.00				MRI STUDIES OF OPTIC PATHWAY GLIOMA IN MOUSE MODELS OF NEUROFIBROMATOSIS-1
	$50,000.00				Time-Resolved Laser Induced Fluorescence Spectroscopy (TRLIFS) to discriminate optic glioma from normal nerve in an astrocyte nf-1 knock out mouse model.
	$50,000.00				Biomimetic microenvironmental niches to study neural stem cell behavior and brain tumorigenesis’
	$45,000.00				The Role of Lysophosphatidic Acid in Glioma Motility and Chemoresistance
	$20,000.00				Role of Tissue Factor in the Hypercoagulability and the Aggressive Phenotype of Malignant Glioma
	$15,000.00				The role of vascularity, proliferation and programmed cell death in the development of vestibular schwannomas in patients with and without Neurofibromatosis Type II
	$10,000.00				Expression of Developmental Genes in Human Gliomas by DNA Microarrays
	$10,000.00				The role of somatostatic receptor expression in the development of meningiomas in neurofibromatosis (NF) and non NF I patients
	$10,000.00				Cytogenetic Characterization of Neuroblastomas and Menigiomas through multicolor FISH: associating prognostic and chromosome profile
	$10,000.00				Interaction of arsenic trioxide with neuronal cells: tumor and non-tumor models.