12th Edition
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Page xiv under the Personalized Help box insert the following:
Top First Things
The most important, immediate issues upon diagnosis can be found in a Checklist of the Top Ten First Things found starting on Page 82 of this Guide.
 -  Page 9 (as shown at the bottom of the page), last paragraph under the heading "Mutations in IDH-1 and IDH-2".  Replace the last sentence in its entirety with this sentence:
Such tumors in adults with an absence of the ATRX protein and an abundance of p53 protein are diagnosed as astrocytomas.
 -  Page 347,  under the table.  Replace the text and link as follows:
An organization called Gliogene is engaged in a study of familial brain tumors. A link to their site is:
https://med.stanford.edu/bondylab/projects/gliogene-project.html