This section of our web site attempts to explain the latest brain tumor treatments that are in general use in plain English, with a brief overview of each, then details on the treatments and where to find them. Unlike the rest of the "Clinical Trials & Noteworthy Treatments For Brain Tumors" site, this section is only the authors' OPINIONS of the material. Use it for general information, to get ideas of what is available out there, but then discuss it with your own doctors.

If you disagree with anything said, have anything to add, or want to help write a topic, please let us know.

This section is updated frequently - so check back often!

Some of the papers are in PDF format. These require you to have installed the free PDF plug-in from Most new computers already have it. If your computer can't open the file, go to and download the Adobe Acrobat Reader, then return here.

For the papers in PDF format, they will open up full screen without our menu at top. To get back here, just use the BACK button on your browser, or the backspace key.

  1. Metastatic Brain Tumors - Michael Schulder, MD Added 7/31/2020

  2. Highlights From ASCO 2020 (discuss them in our forum!) Added 5/30/2020

    1. Al Musella's ASCO Highlights Part 1

    2. Al Musella's ASCO Highlights Part 2

    3. Patrick Wen's Highlights

    4. ASCO 2020: Abstract Recommendations From Dr. Roger Stupp for Brain Cancer

  3. Al Musella's thoughts on what he would do if he had a newly diagnosed gbm.

  4. Treatment Options for Glioblastomas AND The Role of Supplements (including Anti-Oxidants) in Cancer Treatment By Ben Williams, Ph.D. (Experimental Psychology) ** Updated Aug 2017 READ THIS FIRST!

  5. ONC-201 - an oral experimental treatment in clinical trials

  6. Articles by Stephen Western of Astrocytoma

  7. Bevacizumab (Avastin) updated: 04/19/2020

  8. Cancer and Evolution updated: 04/19/2020

  9. Currently Recruiting Clinical Trials - Glioblastoma updated: 04/19/2020

  10. Currently Recruiting Clinical Trials - High Grade Glioma updated: 04/19/2020

  11. Currently Recruiting Clinical Trials - Low Grade Glioma updated: 04/19/2020

  12. Dasatinib (Sprycel) updated: 04/19/2020

  13. DCVax (and other dendritic cell vaccines) updated: 04/19/2020

  14. Diet updated: 04/19/2020

  15. Glossary of brain tumor terms updated: 04/19/2020

  16. Immunotherapy updated: 04/19/2020

  17. NovoTTF (Electric Field Therapy) updated: 04/19/2020

  18. PCV chemotherapy updated: 04/19/2020

  19. Photodynamic Therapy updated: 04/19/2020

  20. Re-educating the Immune System updated: 04/19/2020

  21. Repurposed Drugs updated: 04/19/2020

  22. SNO 2014 Highlights updated: 04/21/2019

  23. SNO 2016 Clinical Highlights updated: 04/19/2020

  24. Supplements updated: 04/19/2020

  25. Targeting Glioma Stem Cells updated: 04/21/2019

  26. Targeting Tumor Associated Macrophages/Microglia updated: 04/19/2020

  27. Targeting Tumor Invasion updated: 04/19/2020

  28. Targeting Tumor Metabolism updated: 04/19/2020

  29. Temozolomide (Temodar) updated: 04/19/2020

  30. The Blood-Brain Barrier updated: 04/19/2020

  31. Toca 511 And Toca FC updated: 04/19/2020

  32. Trial Results - Anaplastic Glioma updated: 04/19/2020

  33. Trial Results - Anaplastic Glioma - Recurrent updated: 04/19/2020

  34. Trial Results - Glioblastoma updated: 04/19/2020

  35. Trial Results - Glioblastoma - Recurrent updated: 04/21/2019

  36. Trial Results - Oligodendroglioma And Oligoastrocytoma updated: 04/19/2020

  37. Virotherapy updated: 04/19/2020

  38. Gliadel Overview updated: 04/19/2020

  39. Leading Edge Radiosurgery (12/2016) Among the best reported results!

  40. Three-dimensional Exoscope for Brain Tumor Surgery

  41. Introduction to Radiosurgery (added 2/24/18)

  42. Transcript of the FDA meeting for the approval of the Novo TTF 100A device (Optune). (This is a huge file - may take time to open)

  43. What is CED (Convection Enhanced Delivery)? This is a new form of CED that can be used long term.(added 10/28/2010)

  44. Article on the possible link between viruses - like CMV - and brain tumors

  45. Avastin

  46. CPT-11 and Avastin for malignant glioma. - early report on a promising new combinaton therapy!

  47. Avastin and CPT-11, Etoposide or Carboplatin Amazing early results. This one is a must read. Look at the results in the table for thos who used Avastin + CPT-11
  48. Human Corticotropin-Releasing Factor (hCRF) (Xerecept) in Peritumoral Brain Edema - a possible replacement for Decadron!
    By Lisa U. Carr, MD, PhD

  49. Medulloblastomas

  50. Atypical Teratoid Rhabdod Rumor (AT/RT).

  51. Neuroblate System - Laser surgery

  52. Vaccine Therapies for Brain Tumors

  53. Proton Beam Radiation (this is a .pdf file and requires the free pdf reader)

  54. Abstracts from ASCO 2007 (Reported by Hong Lan) Old but interesting!

  55. Email Communication for Patients with a life-threatening illness - one way of dealing with keeping the family "in the loop"!

  56. Update to Social Security Disability Rules

  57. Brain Metastases - an overview (last updated 2/18/18)

  58. The Anti-angiogenic basis of metronomic chemotherapy. (added 7/29/2004) - Doesn't specifically mention brain tumors, but there are trials of this approach going on now with brain tumors.This paper (which is on the technical side) explains the rationale for this approach.

  59. Future options of anti-angiogenic cancer therapy

  60. Boron Neutron Capture Therapy:

  61. Boron Neutron Capture Therapy (BNCT) of Brain Tumors. (Note - this is also on the technical side and is a large file.) Added 8/24/2004

  62. Introduction to the special edition of the Journal of Neuro-Oncology on Boron Neutron Capture Therapy(BNCT). (Note - this is on the technical side - but points to a lot of information on this treatment.)
  63. Brain Tumor Guide - Newly diagnosed people should start here first to get an overview of everything before exploring the rest of this website!

  64. Brain Tumor Symptoms: Overview | Detailed

  65. 'Leading Edge' Gamma Knife radiosurgery for primarymalignant brain tumors.- this is a new way of using the gamma knife.. this paper is in a pdf. See instructions above if you have a problem loading the paper.

  66. Immunotherapy for brain tumors. 2 papers by Dr. Roberta Hayes

  67. Temodar® (Temozolomide) For Brain Tumors:
  68. General Information

  69. Review
    By Andrew Parker

  70. Recent papers and abstracts on Temodar
  71. Medulloblastoma

  72. What is a Karnofsky Score?

  73. High Dose Tamoxifen For Brain Tumors:
  74. Review
    By Andrew Parker (Updated 6/8/2004)

  75. Reprint of Research Paper
    By William Couldwell, MD, PhD.
    NY Medical College, Valhalla, NY
  76. Brain Tumor Virtual Trial Abstract about our study!

  77. Seizures: What to do if you are having a seizure!

  78. CPT-11
    By Virginia V. Jory, Ph.D.

  79. PCV
    By Danita Acquafredda And George Hunter

  80. BCNU

  81. What Are Clinical Trials
    By Terri Armstrong, RN, MS, NP, CS
    Neuro-Oncology Nurse Practitioner
    Emory University, Atlanta, Georgia

  82. Childhood Hydrocephalus: Clinical Features, Treatment, and the Slit-Ventricle Syndrome Explanation of the use of shunts, by Dr. Arno Fried.

  83. 50 Questions to help communicate with people who can't talk. By Jim Kenzig

  84. Thoughts on Alternative Treatments
    Guest editorial by Dr. Robert Fink
    Click HERE for a list of FAQs and articles about brain tumors by Dr. Fink.

    Disclaimer: The material provided here is controversial and is only the opinion of the person noted as author of a topic. It is provided for informational purposes only and should not be considered as medical advice or instruction.
    Consult your health care professional for advice relating to a medical problem or condition.