Brain Tumor News!

Note: The comments under each article title are the opinion of our president, Al Musella, DPM,
and do not reflect official policy of the Musella Foundation!

06/24/02 PET Helps Predict Primary Brain Cancer Survival        

06/12/02 Terminally ill woman and family await donations to take dream trip        

06/05/02 LHHS Subcommittee Hearing -- Testimony of Steve Case Presentation of an interesting plan to speed up the search for the cure!        

06/03/02 Mason earns spot on Senior PGA Tour
He donated his $34,000 top prize to the Brain Tumor Foundation for Children!        

06/03/02 Custom-Made Wigs for Cancer Sufferers        

06/03/02 Bikers put in miles so ill kids can smile        

06/03/02 Advectus Life Sciences Inc. - Pre-clinical brain cancer collaboration        

06/01/02 SuperGen's Partaject(TM)-Delivered Busulfan is Safe and Effective in Patients with Neoplastic Meningitis
Results from Phase I clinical trial presented at 38th Annual Meeting of the American Society of Clinical Oncology (ASCO)        

05/30/02 Jeffery Williams, Hopkins’ Neurosurgeon, Dies at 50        

05/29/02 Sosei Licenses TransMID from KS Biodex        

05/28/02 COX-2 Inhibition May Stop Meningioma Development        

05/26/02 Gliomas following organ transplantation: a tumor registry analysis: No evidence that primary brain tumors are found more frequently in transplant recipients relative to population.        

05/26/02 Overexpression of c-kit oncogene in human brain tumors Positive correlation between c-kit, a transdermal glycoprotein and more aggressive brain malignancy could lead to c-kit targeted therapies to treat high grade gliomas        

05/26/02 Safety profile and activity of high-dose temozolomide given daily x 3 every 2 weeks in patients with primary brain tumors. Temador was given safely at escalated dosages on days 1-3 and 14-16 every 28 days.        

05/26/02 Intratumoral and intracerebral microinfusion of IL13-PE38QQR cytotoxin: phase I/II study of pre-and post-resection infusions in recurrent resectable malignant glioma. Chemotherapy directed at both the tumor site following biopsy and to brain tissue adjacent to operative site following resection.        

05/26/02 Neoadjuvant chemotherapy with fluvastatin, carboplatin and vincristine for the treatment of low grade astrocytomas (LGA): a phase II study Pediatric study of low grade astrocytomas showed good response with the addition of fluvastatin to chemotherapy regimen of carboplatin and vincristine; due to small sample size, more studies needed.        

05/26/02 Quality of life (QOL) and sexual function in brain tumor (BT) patients Compared between patients who received radiotherapy (RT) as part of brain tumor treatment and patients who did not receive RT regarding depression, menstrual irregularities and sexual function.        

05/26/02 Randomized phase II study of temozolomide (TMZ) with and without the matrix metalloprotease (MMP) inhibitor prinomastat in patients (pts) with glioblastoma multiforme (GBM) following best surgery and radiation therapy No significant difference between survival rate of pt treated with temodar + prinomastat vs temodar + placebo.        

05/26/02 Concurrent chemoradiotherapy in chemo- naive operated glioblastoma multiforme: a phase II study Pts given Docetaxel on first treatment day of each radiotherapy (RT) week with survival rate comparable to treatment plan of chemotherapy after RT.        

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