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This study shows that biopsy of DIPG is not as dangerous as we thought. Years ago it was never done due to the dangers involved but with advances in pediatric neurosurgery, this study shows that in 53 patients, 2 had problems in surgery that resolved, and only 1 had long term neurological deficit. Of course if you are that one out of 53, it is horrible, but kids with this tumor all develop neuro problems and most die quickly. In the past it was not worth the risk as even if they were able to do a biopsy, it wouldn't matter much as there were no treatments anyway. Now we have access to a lot of targeted treatments that may help.