This is a very scary article. Most young adult patients did not continue to work after a high grade glioma diagnosis. I feel that this should be one of the endpoints in all clinical trials: is the patient able to work at the level they did before the diagnosis? In the past, unfortunately, most patients did not return to work after the diagnosis. Many who did were not able to work full time or in the same capacity as before. 2 years after diagnosis it was unheard of for patients to be working at a high level job.
So now as we are seeing more long term survivors with Optune and some experimental treatments, we now need to know their quality of life. Being able to work is a very important quality of life marker. I have come into contact with a few patients recently who are able to work at high pressure jobs, just like before their diagnosis, over 5 years since diagnosis. This was very rare before, so it is a significant finding for any trials.