Al's Comment:

 This is early results on a small number of patients but the results are very good. They started with newly diagnosed patients with unmethylated MGMT who did not have a complete resection.  They had only  a biopsy or a debulking.  This is the worst subset of Glioblastoma.  They report of 6 patients, 5 out of the 6 are alive at the 15 month point, and 1 had a complete response, 2 had a 99% response, and 2 had a partial response that was durable!   It is very rare to see complete response or 99% response in MGMT unmethylated patients.   The trial is ongoing and worth considering for Glioblastoma patients with MGMT unmethylated.


Posted on: 07/18/2023

NOX-A12 Plus Radiotherapy and Bevacizumab Produces Responses in Previously Untreated Glioblastoma

 

 


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