This is one of my favorite trials. We did a webinar about it a few years ago https://virtualtrials.org/video2022.cfm?video=202205 and will probably do another in the next few months. They have a trial going for recurrent grade 3 and 4 gliomas (Glioblastoma, Anaplastic Astrocytoma, High grade diffuse glioma), and this guide gives the details about the trial.