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Leptomeningeal spread is when the cancer spreads to the lining of the brain and/or spinal cord. A big problem with it is that most clinical trials will exclude you if you have leptomeningeal spread, and there are no approved treatments that really help much. However, there is an exciting clinical trial about to open that uses Car-t cell therapy to try to treat leptomenigeal spread. If you are interested in details, contact me. When the trial opens I will announce it in a news blast.