Al's Comment:

This is a confusing study. It goes against what we thought was true about using temozolomide. This study was in anaplastic astrocytomas, and showed that there is very little benefit in using temozolomide at the same time as radiation but there is a large benefit using it after radiation.  However, that only applies to certain subgroups.   In some subgroups of patients temozolomide did not help at all.  We will be having a webinar next month on a new test that should simplify this and better predict which patients would benefit from Temozolomide or other treatments.

Posted on: 06/25/2021

Adjuvant - Not Concurrent - Temozolomide Upped Overall Survival in 1p/19q Non - Co-Deleted Anaplastic Glioma: Commentary on the CATNON Trial


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