Al's Comment:

 We (The Musella Foundation with the help of our fantastic donors!) helped fund this research project.  They found that just adding a drug that inhibits the main way the Glioblastoma cells move did not really help much. In fact, they found that the cells easily and quickly used a different mechanism to move.  Combining inhibitors of both pathways did help. A lot, but not completely -  a 3rd drug might be needed to target the resistance pathway.  They did find a biomarker in the blood that may predict recurrence of Glioblastoma. More work needs to be done to validate the biomarker and to completely eliminate invasion! Good work!

 


Posted on: 01/04/2022

Drug Resistance in Glioma Cells Induced by a Mesenchymal-Amoeboid Migratory Switch

 


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