This is one of my favorite new treatments. Very elegant. You get a dye injected IV which preferentially concentrates in the tumor. Then focused ultrasound is applied using a helmet like device for a few minutes. This activates the dye which kills the tumor cells. It is noninvasive (other than the injection into the arm) and can be repeated if needed. The Clinical trial for DIPG is now open, and the trial for recurrent Glioblastoma will open soon. I will be watching this closely and wish them luck.