Al's Comment:

I love research like this. First they figure out how cytotoxic T lymphocytes kill tumor cells. Then they figured out how the tumor cells defended themselves against the T cells.  Then they figured out a way to suppress the defense mechanism, and made the T cells work dramatically better.   The problem is the defense mechanism is also used by normal dividing cells so in this case it might be difficult to create a drug to this vulnerability.  But they are working on it and think they can ultimately solve the problem! I wish them luck.


Posted on: 07/23/2022

Genentech-led team uncovers how cancer cells resist T-cell attack in potential boon to immunotherapy

 


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