This University of Miami study used daily non-contrast MRIs with a ViewRay MRI-linear accelerator (MR-linac) to deliver radiation therapy to glioblastoma (GBM) patients. The results suggest this technique can be used for adaptive radiotherapy, where radiation oncologists can rapidly modify treatment plans based on observed tumor changes or surgical cavity shrinkage. While this study used non-contrast MRIs, this method could also be used to guide decisions on when a mid-radiation contrast MRI might be warranted for treatment adjustments. Only a few medical centers across the country offer this radiation approach, but we hope to see broader adoption and availability in coming years.